Whether or not you run experiments, there are elements of experimental design that affect how you need to analyze many types of studies.
The most fundamental of these are replication, randomization, and blocking. These key design elements come up in studies under all sorts of names: trials, replicates, multi-level nesting, repeated measures. Any data set that requires mixed or multilevel models has some of these design elements. (more…)
What is a Confounder?
Confounder (also called confounding variable) is one of those statistical terms that confuses a lot of people. Not because it represents a confusing concept, but because of how it’s used.
(Well, it’s a bit of a confusing concept, but that’s not the worst part).
It has slightly different meanings to different types of researchers. The definition is essentially the same, but the research context can have specific implications for how that definition plays out.
If the person you’re talking to has a different understanding of what it means, you’re going to have a confusing conversation.
Let’s take a look at some examples to unpack this.
Oops—you ran the analysis you planned to run on your data, carefully chosen to answer your research question, but your residuals aren’t normally distributed.
Maybe you’ve tried transforming the outcome variable, or playing around with the independent variables, but still no dice. That’s ok, because you can always turn to a non-parametric analysis, right?
Well, sometimes.
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The expression “can’t see the forest for the trees” often comes to mind when reviewing a statistical analysis. We get so involved in reporting “statistically significant” and p-values that we fail to explore the grand picture of our results.
It’s understandable that this can happen. We have a hypothesis to test. We go through a multi-step process to create the best model fit possible. Too often the next and last step is to report which predictors are statistically significant and include their effect sizes.
Every statistical model and hypothesis test has assumptions.
And yes, if you’re going to use a statistical test, you need to check whether those assumptions are reasonable to whatever extent you can.
Some assumptions are easier to check than others. Some are so obviously reasonable that you don’t need to do much to check them most of the time. And some have no good way of being checked directly, so you have to use situational clues.
When I was in graduate school, stat professors would say “ANOVA is just a special case of linear regression.” But they never explained why.
And I couldn’t figure it out.
The model notation is different.
The output looks different.
The vocabulary is different.
The focus of what we’re testing is completely different. How can they be the same model?